Methyl iodide → 7-Amino-2-methyl-3,4-dihydroisoquinolinium iodide
反応式
[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][N:8]=[CH:9]2)=[CH:4][CH:3]=1.[I:12][CH3:13]>CC(C)=O>[I-:12].[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][N+:8]([CH3:13])=[CH:9]2)=[CH:4][CH:3]=1参加物
4
実験手順
7-amino-3,4-dihydroisoquinoline (0.40 g, 2.74 mmol) in acetone (125 ml) was treated with iodomethane (0.50 ml, 8.03 mmol) and left stirring at room temperature for 18 h. The resultant yellow precipitate was collected by filtration and dried in vacuo at ambient temperature (0.73 g, 92%). m/z (API)=161 (M)+
後処理
- waitleft
- filtrationThe resultant yellow precipitate was collected by filtration
- customdried in vacuo at ambient temperature (0.73 g, 92%)
出典と根拠
- ORDレコード
- ord-a31009c6874141d691607b362acda856
- 出典データセット
- uspto-grants-2001_08
- 特許番号
- US06277861B1
反応ノート
読み込み中…