Itaconic acid → 3-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid

HRID 65123

反応式

HRID 65123 の反応式
[Al+3].[Cl-].[Cl-].[Cl-].[SH:5][C:6]1[S:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=1.[C:15]([OH:23])(=[O:22])[C:16]([CH2:18][C:19]([OH:21])=[O:20])=[CH2:17].O>C(OCC)C.C(OCC)(=O)C>[S:7]1[C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=[C:6]1[S:5][CH2:17][CH:16]([C:15]([OH:23])=[O:22])[CH2:18][C:19]([OH:21])=[O:20]

参加物

7

反応物 4

HCID 811Itaconic acidHCID 962WaterHCID 6451240Aluminum(III) ChlorideHCID 178418395HCID 178418395、化合物

生成物 1

HCID 194275373-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid収率 50.5%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒2 回HCID 8857Ethyl Acetate溶媒

実験手順

13.3 g of AlCl3 are dissolved in 100 ml of diethyl ether at 0° to 5°. 3.4 g of 2-mercaptobenzothiazole and 2.6 g of itaconic acid are then added. After the mixture has been stirred at 20°-25° for 24 hours, the ether solution is poured off and the residue is stirred with 100 ml of water and 100 ml of ethyl acetate. The organic phase is separated off, dried and evaporated. 3 g of 3-(benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid are obtained as the residue.

後処理

  1. customThe organic phase is separated off
  2. customdried
  3. customevaporated

出典と根拠

ORDレコード
ord-7b1fd30bd3da47a381b20f84f472db06
出典データセット
uspto-grants-1986_09
特許番号
US04612378

関連ノート

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