Hydrochloric Acid → HCID 821134、化合物
反応式
[CH2:1]([O:3][C:4](=[O:17])[NH:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][C:7]=1[N+:14]([O-])=O)[CH3:2].Cl.[H][H]>CCO.[Pd]>[CH2:1]([O:3][C:4](=[O:17])[NH:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][C:7]=1[NH2:14])[CH3:2]参加物
6
実験手順
A solution of (4-methoxy-2-nitrophenyl)carbamic acid ethyl ester (7.3 g; 0.03 mol) in 95% EtOH (500 ml), was hydrogenated at room temperature and pressure in the presence of 10% aqueous HCl (13 ml) and 10% Pd/C (0.35 g). When the theoretical amount of hydrogen was taken up, the catalyst was filtered off and the solution was evaporated to dryness to give the title compound (5 g) after crystallization from Et2O/EtOH (85:15). The compound was used without further purification.
後処理
- customwas hydrogenated at room temperature
- filtrationthe catalyst was filtered off
- customthe solution was evaporated to dryness
出典と根拠
- ORDレコード
- ord-2cdf3a82ab9b47a38f9eaba01bc8498f
- 出典データセット
- uspto-grants-2001_08
- 特許番号
- US06281218B1
反応ノート
読み込み中…