(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acid → 3-(2,3-Dimethoxyphenyl)propanoic acid

HRID 651556

反応式

HRID 651556 の反応式
[N].[CH3:2][O:3][C:4]1[C:9]([O:10][CH3:11])=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:12][CH2:13][C:14]([OH:16])=[O:15].COC1C(OC)=CC=CC=1/C=C\C(O)=O.[H][H]>CO.[Pd]>[CH3:2][O:3][C:4]1[C:9]([O:10][CH3:11])=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:12][CH2:13][C:14]([OH:16])=[O:15]

参加物

6

反応物 3

HCID 1559386(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acidHCID 178418361HCID 178418361、化合物HCID 178490125HCID 178490125、化合物

生成物 1

HCID 3149293-(2,3-Dimethoxyphenyl)propanoic acid

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

3-(2,3-Dimethoxyphenyl)-propanoic acid Nitrogen was passed through a stirred suspension of (Z)-3-(2,3-dimethoxyphenyl)-2-propenoic acid (14,67 g) in 400 ml of methanol during 15 minutes. Then 1.4 g of 10% palladium on activated carbon were added and a stream of hydrogen was passed through the reaction mixture for 16 hours. After removing the palladium catalyst by filtration, the filtrate was evaporated to yield 14.2 g of 3-(2,3-dimethoxyphenyl)-propanoic acid, M.S. (C.I.) (M/Z): 211 [M+H]+.

後処理

  1. customAfter removing the palladium catalyst
  2. filtrationby filtration
  3. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-79fe34d3f14f41fc93ed74a59c7da1d8
出典データセット
uspto-grants-2001_08
特許番号
US06281243B1

関連ノート

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