Thionyl Chloride → 3-(Chloromethyl)-1,1'-biphenyl
反応式
O[CH2:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1.S(Cl)([Cl:17])=O>>[Cl:17][CH2:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1参加物
3
実験手順
A solution of 50 mg of 3-hydroxymethylbiphenyl in 1.5 mL thionyl chloride was heated at reflux temperature for 4 hr, cooled to room temperature and the solvent removed by evaporation under reduced pressure to yield 45 mg of 3-chloromethylbiphenyl which was used in the next step without further purification or characterization.
後処理
- temperatureat reflux temperature for 4 hr
- customthe solvent removed by evaporation under reduced pressure
出典と根拠
- ORDレコード
- ord-4187c7e7eb114d3eba0842f23595041d
- 出典データセット
- uspto-grants-2001_08
- 特許番号
- US06281359B1
反応ノート
読み込み中…