Nitric Acid → 6-hydroxy-7-nitro-2H-1,4-benzoxazin-3-(4H)-one

HRID 652397ノート

反応式

HRID 652397 の反応式
[N+:1]([O-:4])(O)=[O:2].[OH:5][C:6]1[CH:7]=[CH:8][C:9]2[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=2[CH:16]=1>C(O)(=O)C>[OH:5][C:6]1[C:7]([N+:1]([O-:4])=[O:2])=[CH:8][C:9]2[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=2[CH:16]=1

参加物

4

反応物 2

HCID 944Nitric AcidHCID 113786896-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

生成物 1

HCID 212986856-hydroxy-7-nitro-2H-1,4-benzoxazin-3-(4H)-one

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

Fumic nitric acid (δ1.52, 2.6 ml, 0.062 mole) in acetic acid (5 ml) was added dropwise under stirring to 6-hydroxy-2H-1,4-benzoxazin-3-(4H)-one (Coupler (1), 10.3 g, 0.062 mole) in acetic acid (100 ml) at room temperature. The 6-hydroxy-7-nitro-1,4-benzoxazin-3-one (6.7 g, 51%) separated as yellow prisms.

後処理

  1. customThe 6-hydroxy-7-nitro-1,4-benzoxazin-3-one (6.7 g, 51%) separated as yellow prisms

出典と根拠

ORDレコード
ord-02c7b2acb4b141b38ba9247f01373cc6
出典データセット
uspto-grants-1987_06
特許番号
US04672013

反応ノート

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