1-Methylimidazole → HCID 178480862、化合物

HRID 65251

反応式

HRID 65251 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11]Cl)=[CH:4][CH:3]=1.[CH3:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>>[Cl-:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][N+:16]2[CH:17]=[CH:18][N:14]([CH3:13])[CH:15]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 13901-MethylimidazoleHCID 200827321-Chloro-4-(4-chlorobutyl)benzene

生成物 1

HCID 178480862HCID 178480862、化合物

実験手順

Combine 6.1 g (0.03 mole) 1-chloro-4-(4-chlorobutyl)benzene with 2.5 g (0.03 mole) 1-methyl-1H-imidazole and heat at 120° C., following the course of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5). At the completion of the reaction, cool and triturate with ether, collect the solid and recrystallize from 50 ml hot acetone to obtain the title compound.

後処理

  1. customthe course of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5)
  2. customAt the completion of the reaction
  3. temperaturecool
  4. customtriturate with ether
  5. customcollect the solid
  6. customrecrystallize from 50 ml hot acetone

出典と根拠

ORDレコード
ord-789f015a518643958156a7ed367e7d7e
出典データセット
uspto-grants-1986_09
特許番号
US04613609

関連ノート

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