4-Hydroxybenzaldehyde → HCID 185042、化合物

反応式

[NH2:1]CCC(O)=O.[OH:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=O.[NH2:16][CH2:17][C:18]([OH:20])=O.OC1C=CC([CH:26]=[O:27])=CC=1>>[OH:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=[C:17]1[NH:16][C:26](=[O:27])[NH:1][C:18]1=[O:20]

参加物

反応物 4

HCID 1264-Hydroxybenzaldehyde

HCID 239Beta-Alanine

HCID 750Glycine

HCID 6998Salicylaldehyde

生成物 1

HCID 185042HCID 185042、化合物

実験手順

5-(o-Hydroxybenzylidene)-hydantoin was prepared in the same manner as in Example 4, except that 22.2 g (0.25 mol) of β-alanine and 61.1 g (0.50 mol) of o-hydroxybenzaldehyde were used in lieu of glycine and p-hydroxybenzaldehyde, respectively, and that the reaction time was 6 hours. During the reaction, the pH of the reaction mixture was 9.6 to 9.2.