Water → HCID 4491527、化合物

HRID 652793ノート

反応式

HRID 652793 の反応式
[C:1]([C:5]1[CH:6]=[C:7]([CH:16]=[C:17]([C:20]([CH3:23])([CH3:22])[CH3:21])[C:18]=1[OH:19])[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=O)([CH3:4])([CH3:3])[CH3:2].[C:24]1([NH:30][NH2:31])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1C=CC=CC=1>[C:24]1([NH:30][N:31]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:7]2[CH:6]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:18]([OH:19])=[C:17]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:16]=2)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

参加物

6

反応物 4

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 7516PhenylhydrazineHCID 1898376(3,5-Di-tert-butyl-4-hydroxyphenyl)(phenyl)methanone

生成物 1

HCID 4491527HCID 4491527、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

One gram of 3,5-di-t-butyl-4-hydroxybenzophenone and 880 mg of phenylhydrazine were refluxed under heating in 30 ml of benzene in the presence of 20 mg of p-toluenesulfonic acid for 3.5 hours. The reaction mixture was poured into water and extracted with benzene. The extract was chromatographed on a silica gel column, and recrystallized from diethyl ether/n-hexane to give 3,5-di-t-butyl-4-hydroxybenzophenone phenylhydrazone as colorless needles.

後処理

  1. extractionextracted with benzene
  2. customThe extract was chromatographed on a silica gel column
  3. customrecrystallized from diethyl ether/n-hexane

出典と根拠

ORDレコード
ord-e56ed194e06a4bfcbba6c776a3787d3d
出典データセット
uspto-grants-1987_06
特許番号
US04673692

反応ノート

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