Ammonia → HCID 20195198、化合物

HRID 653206ノート

反応式

HRID 653206 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([S:14](Cl)(=[O:16])=[O:15])[C:5]2[O:10][S:9](=[O:12])(=[O:11])[CH:8]=[CH:7][C:6]=2[CH:13]=1.[NH3:18].Cl>O1CCCC1>[Br:1][C:2]1[CH:3]=[C:4]([S:14](=[O:16])(=[O:15])[NH2:18])[C:5]2[O:10][S:9](=[O:12])(=[O:11])[CH:8]=[CH:7][C:6]=2[CH:13]=1

参加物

5

反応物 3

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 20195206HCID 20195206、化合物

生成物 1

HCID 20195198HCID 20195198、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

The crystalline product obtained in (c) is dissolved in as small an amount of tetrahydrofuran as possible and the solution is added dropwise to 20 ml of 25% aqueous ammonia solution. After the reaction mixture has been stirred for 30 minutes it is poured into a mixture of ice and 10% hydrochloric acid. Extraction with ether yields 0.3 g of 6-bromo-8-sulfamoyl-2,2-dioxo-1,2-benzoxathiine of m.p. 224°-228° C. (decomposition with black colouration).

後処理

  1. extractionExtraction with ether

出典と根拠

ORDレコード
ord-f972fa3e893a49b2ba7c0e638832aae0
出典データセット
uspto-grants-1987_06
特許番号
US04675417

反応ノート

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