Toluene → L-Phenylalanine, methyl ester

HRID 65322

反応式

HRID 65322 の反応式
[C:1]1(C)C=CC=CC=1.[OH-].[Na+].[NH2:10][C@H:11]([C:19]([OH:21])=[O:20])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[CH3:1][O:20][C:19](=[O:21])[C@H:11]([CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[NH2:10]

参加物

5

反応物 3

HCID 1140TolueneHCID 6140L-PhenylalanineHCID 14798Sodium Hydroxide

生成物 1

HCID 736234L-Phenylalanine, methyl ester

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A 0.2 molar solution phenylalanine methyl ester in 10 milliliters of water was prepared. Toluene was added and the pH of the system adjusted to 7.0 with sodium hydroxide. Chymotrypsin in the amount of 1 milligram was added. The concentration of phenylalanine in the aqueous phase was monitored. The initial concentration was 0.05 molar and the final concentration at the end of the hydrolysis was 0.15 molar, consistent with only one isomer being extracted.

後処理

  1. additionChymotrypsin in the amount of 1 milligram was added
  2. concentrationThe initial concentration was 0.05 molar and the final concentration at the end of the hydrolysis
  3. extractionconsistent with only one isomer being extracted

出典と根拠

ORDレコード
ord-f97a0b57cff94a51a3997dbb76557cb3
出典データセット
uspto-grants-1986_09
特許番号
US04613691

関連ノート

読み込み中…