Hydrazine hydrate (1:1) → 3-Hydrazinyl-4-methyl-6-phenylpyridazine
反応式
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8].O.[NH2:16][NH2:17]>>[NH:16]([C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8])[NH2:17]参加物
3
実験手順
The mixture of 5 g of 3-chloro 4-methyl 6-phenyl pyridazine and 12 ml of hydrazine hydrate is taken to reflux. After one hour thirty minutes, the reaction medium is left to cool. A solid separates, which is drained and washed with a little water. The product is recrystallized in the mixture of isopropanol-isopropyl ether. Weight 4.5 g. m.p.: 162° C.
後処理
- temperatureto reflux
- waitthe reaction medium is left
- temperatureto cool
- washwashed with a little water
- customThe product is recrystallized in the mixture of isopropanol-isopropyl ether
出典と根拠
- ORDレコード
- ord-c4dae93679be429abc4e17c9eda49f3b
- 出典データセット
- uspto-grants-1987_06
- 特許番号
- US04677106
反応ノート
読み込み中…