化工社化工社 化学情報印刷レポート · 研究参考用
m-Chloroperbenzoic acid → HCID 178437532、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 反応物 | 2-ethyl-7-methyl-3H-Imidazo[4,5-b]pyridine | HCID 18693036 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | HCID 178437532 | HCID 178437532 | — |
反応手順
A solution of 28 g (174 mmol) of 2-ethyl-7-methylimidazo[4,5-b]pyridine (prepared according to Example 1, Steps A and B, but substituting propionic acid in place of butyric acid in Step B) and m-chloroperbenzoic acid (80-90%, 44.6 g) in CHCl3 (300 mL) was heated at reflux for 0.5 hours. The mixture was concentrated and purified (SiO2, 100% CH2Cl2 gradient to 30% CH2Cl2 /MeOH) to give the title compound as a solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05128327 |
| 出典データセット | uspto-grants-1992_07 |
| ORD ID | ord-96427f73bd874766b4fd642331706e32 |
| 出典メモ | uspto-grants-1992_07 |