Monobasic potassium phosphate → Ribavirin

HRID 65428

反応式

HRID 65428 の反応式
[NH:1]1[CH:5]=[N:4][C:3]([C:6]([NH2:8])=[O:7])=[N:2]1.[O:9]=[CH:10][C@@H:11]([C@@H:13]([C@@H:15]([CH2:17][OH:18])[OH:16])[OH:14])O.P([O-])(O)(O)=O.[K+]>>[CH:5]1[N:1]([C@@H:17]2[O:18][C@H:11]([CH2:10][OH:9])[C@@H:13]([OH:14])[C@H:15]2[OH:16])[N:2]=[C:3]([C:6]([NH2:8])=[O:7])[N:4]=1

参加物

4

反応物 3

HCID 516951Monobasic potassium phosphateHCID 5311110Aldehydo-D-riboseHCID 178513825HCID 178513825、化合物

生成物 1

HCID 37542Ribavirin

実験手順

To each cell suspension was added each 1 ml of an aqueous solution (pH 7.0) containing 20 mM 1,2,4-triazole-3-carboxamide, 20 mM of each of the various ribose donors as shown in Table 3 and 25 mM of monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 24 hours. After completion of the reaction, the cells were removed by centrifugation, and the supernatant was analyzed to obtain the results of ribavirin yield as shown in Table 3.

後処理

  1. customAfter completion of the reaction
  2. customthe cells were removed by centrifugation
  3. customto obtain the

出典と根拠

ORDレコード
ord-9e8e654260814970a075e1d7bf3a873c
出典データセット
uspto-grants-1986_09
特許番号
US04614719

関連ノート

読み込み中…