Monobasic potassium phosphate → Ribavirin

HRID 65430

反応式

HRID 65430 の反応式
[NH:1]1[CH:5]=[N:4][C:3]([C:6]([NH2:8])=[O:7])=[N:2]1.P([O-])(O)(O)=O.[K+].[O:15]=[CH:16][C@@H:17]([C@@H:19]([C@@H:21]([CH2:23][OH:24])[OH:22])[OH:20])O>>[CH:5]1[N:1]([C@@H:23]2[O:24][C@H:17]([CH2:16][OH:15])[C@@H:19]([OH:20])[C@H:21]2[OH:22])[N:2]=[C:3]([C:6]([NH2:8])=[O:7])[N:4]=1

参加物

4

反応物 3

HCID 516951Monobasic potassium phosphateHCID 5311110Aldehydo-D-riboseHCID 178513825HCID 178513825、化合物

生成物 1

HCID 37542Ribavirin

実験手順

To each suspension was added each 1 ml of an aqueous solution (pH 7.0) containing 20 mM 1,2,4-triazole-3-carboxamide, 20 ml of various ribose donors as shown in Table 10 and 25 mM monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 20 hours. After the reaction, the microbial cells were removed by centrifugation and the supernatant was analyzed to give the results of ribavirin yields as shown in Table 10.

後処理

  1. customAfter the reaction
  2. customthe microbial cells were removed by centrifugation
  3. customto give the

出典と根拠

ORDレコード
ord-0e3c0a1ca247400ea7570e83d8abcee8
出典データセット
uspto-grants-1986_09
特許番号
US04614719

関連ノート

読み込み中…