Methallyl alcohol → 2,4,5-Trifluoro-6-methallyloxyisopthalonitrile

HRID 65456

反応式

HRID 65456 の反応式
F[C:2]1[C:7]([C:8]#[N:9])=[C:6]([F:10])[C:5]([C:11]#[N:12])=[C:4]([F:13])[C:3]=1[F:14].[CH3:15][C:16]([CH2:18][OH:19])=[CH2:17].[F-].[K+]>C(#N)C>[F:10][C:6]1[C:5]([C:11]#[N:12])=[C:4]([F:13])[C:3]([F:14])=[C:2]([O:19][CH2:18][C:16](=[CH2:15])[CH3:17])[C:7]=1[C:8]#[N:9]

参加物

5

反応物 3

HCID 10557Methallyl alcoholHCID 522689Potassium FluorideHCID 608182Tetrafluoroisophthalonitrile

生成物 1

HCID 137155472,4,5-Trifluoro-6-methallyloxyisopthalonitrile

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

The mixture of 3.0 g of tetrafluoroisophthalonitrile, 1.2 g of β-methallyl alcohol and 1.8 g of potassium fluoride in 30 ml of acetonitrile was stirred at room temperature for 10 hours. The mixture was cooled and filtered. The filtrate was evaporated under reduced pressure. After 50 ml of water was added to the residue, the mixture was extracted with carbon tetrachloride, washed with water, and dried over sodium sulfate. After evaporating carbon tetrachloride, the residue of 2.9 g (crystal) was obtained.

後処理

  1. temperatureThe mixture was cooled
  2. filtrationfiltered
  3. customThe filtrate was evaporated under reduced pressure
  4. additionAfter 50 ml of water was added to the residue
  5. extractionthe mixture was extracted with carbon tetrachloride
  6. washwashed with water
  7. dry with materialdried over sodium sulfate
  8. customAfter evaporating carbon tetrachloride
  9. customthe residue of 2.9 g (crystal) was obtained

出典と根拠

ORDレコード
ord-7831062aa16349ff9fea5a3d81370c9c
出典データセット
uspto-grants-1986_09
特許番号
US04614742

関連ノート

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