反応式
[CH2:1]1[CH:5]2[CH:6]([C:8]3[O:12][N:11]=[C:10]([NH2:13])[N:9]=3)[CH2:7][N:3](C2)[CH2:2]1.F[C:15](F)(F)[C:16](O)=O.[CH3:21][CH:22](O)[CH3:23].[O:25]=[C:26]([C:28](=[O:30])[OH:29])[OH:27]>ClCCl.ClCCl.CO>[C:28]([OH:30])(=[O:29])[C:26]([OH:27])=[O:25].[CH2:21]([N:13]([CH2:26][C:15]#[CH:16])[C:10]1[N:9]=[C:8]([C:6]2[CH2:7][NH:3][CH2:2][CH2:1][CH:5]=2)[O:12][N:11]=1)[C:22]#[CH:23]参加物
7
実験手順
The foregoing oxadiazole (135 mg, 0.00039 mol) was stirred with trifluoroacetic acid (0.18 mL, 0.0024 mol) in dichloromethane (6 mL) for 24 hours. The hydrogen oxalate salt had mp 134°-135° C. (propan-2-ol). Rf=0.78 in dichloromethane/methanol (9:1) on alumina plates. Mass Spectrum, m/z 242 for M+ of free base. (Found: C, 53.87; H, 4.90; N, 16.52. C13H14N4O. C2H2O4 requires C, 54.21; H, 4.85; N, 16.86%).
出典と根拠
- ORDレコード
- ord-b3091bf1d1f0497e859f22f0ae4c5e0e
- 出典データセット
- uspto-grants-1992_07
- 特許番号
- US05134146
関連ノート
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