4-(3-Pyridyl)cyclohex-3-en-1-one ethylene acetal → 4-(3-Pyridyl)cyclohexanone ethylene acetal
反応式
[CH2:1]1[O:16][C:4]2([CH2:9][CH2:8][C:7]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)=[CH:6][CH2:5]2)[O:3][CH2:2]1>CCOC(C)=O.[Pd]>[CH2:2]1[O:3][C:4]2([CH2:5][CH2:6][CH:7]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)[CH2:8][CH2:9]2)[O:16][CH2:1]1参加物
4
実験手順
A mixture of 4-(3-pyridyl)cyclohex-3-en-1-one ethylene acetal (4.80 g, 22.1 mmol) in EtOAc (50 mL) containing 10% Pd/C (458 mg) was hydrogenated under atmospheric pressure for 3 h. After filtration of the catalyst, the solution was concentrated in vacuo, to yield 4-(3-pyridyl)cyclohexanone ethylene acetal (4.81 g, 99%) as yellow solid.
後処理
- filtrationAfter filtration of the catalyst
- concentrationthe solution was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-aeafbf19eef1400b9856273dd5efa6b4
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08071591B2
反応ノート
読み込み中…