2-Methylcyclohexanone → Methyl 3-(1-methyl-2-oxocyclohexyl)propanoate

反応式

[CH3:1]C1CCCCC1=O.CC1CCCC1=O.[CH3:16][O:17][C:18](=[O:28])[CH2:19][CH2:20][C:21]1([CH3:27])[CH2:25][CH2:24][CH2:23][C:22]1=[O:26]>>[CH3:16][O:17][C:18](=[O:28])[CH2:19][CH2:20][C:21]1([CH3:27])[CH2:25][CH2:24][CH2:23][CH2:1][C:22]1=[O:26]

参加物

反応物 3

HCID 114192-Methylcyclohexanone

HCID 142652-Methylcyclopentanone

HCID 122918891-Methyl-2-oxocyclopentanepropionic acid methyl ester

生成物 1

HCID 574325Methyl 3-(1-methyl-2-oxocyclohexyl)propanoate

実験手順

In the same manner but replacing 2-methylcyclohexanone with an equivalent amount of 2-methylcyclopentanone, 1-methyl-2-oxocyclopentanepropionic acid methyl ester, bp 88°-100° C./1.1 mm, nmr (CDCl3) δ 1.0 (s, 3H), 1.8 (m, 6H), 2.3 (m, 4H), 3.7 (s, 3H), is obtained.