Piperonyl alcohol → 1,3-Benzodioxole, 5-(chloromethyl)-

HRID 65699

反応式

HRID 65699 の反応式
S(Cl)([Cl:3])=O.[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10]O)=[CH:8][C:7]=2[O:6]1>>[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10][Cl:3])=[CH:8][C:7]=2[O:6]1

参加物

3

反応物 2

HCID 10322Piperonyl alcoholHCID 24386Thionyl Chloride

生成物 1

HCID 887131,3-Benzodioxole, 5-(chloromethyl)-

実験手順

153.9 g (1.29 mols) of thionyl chloride are poured onto 65.6 g (0.431 mol) of 3,4-methylenedioxybenzyl alcohol. The mixture is stirred for 90 minutes at ambient temperature (15°-25° C.) and the excess thionyl chloride is then evaporated. The residue is taken up in dimethylformainde (DMF) and the latter is then evaporated. Finally, the residue is taken up in 500 ml of DMF (it is not necessary to isolate the 3,4-methylenedioxybenzyl chloride thus obtained).

後処理

  1. customthe excess thionyl chloride is then evaporated
  2. customthe latter is then evaporated

出典と根拠

ORDレコード
ord-6894a54152924af49879deb8373082ee
出典データセット
uspto-grants-1978_12
特許番号
US04128656

関連ノート

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