Piperonyl alcohol → 1,3-Benzodioxole, 5-(chloromethyl)-
反応式
S(Cl)([Cl:3])=O.[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10]O)=[CH:8][C:7]=2[O:6]1>>[CH2:5]1[O:15][C:14]2[CH:13]=[CH:12][C:9]([CH2:10][Cl:3])=[CH:8][C:7]=2[O:6]1参加物
3
実験手順
153.9 g (1.29 mols) of thionyl chloride are poured onto 65.6 g (0.431 mol) of 3,4-methylenedioxybenzyl alcohol. The mixture is stirred for 90 minutes at ambient temperature (15°-25° C.) and the excess thionyl chloride is then evaporated. The residue is taken up in dimethylformainde (DMF) and the latter is then evaporated. Finally, the residue is taken up in 500 ml of DMF (it is not necessary to isolate the 3,4-methylenedioxybenzyl chloride thus obtained).
後処理
- customthe excess thionyl chloride is then evaporated
- customthe latter is then evaporated
出典と根拠
- ORDレコード
- ord-6894a54152924af49879deb8373082ee
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04128656
反応ノート
読み込み中…