Sodium Hydroxide → HCID 178518977、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:12]([O-:14])=O)=[C:6]([NH:8][C:9]([NH2:11])=[O:10])[CH:7]=1.[OH-].[Na+]>O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N+:12]([O-:14])=[N:11][C:9](=[O:10])[NH:8][C:6]=2[CH:7]=1参加物
4
実験手順
A suspension of N-(5-chloro-2-nitrophenyl)urea (1.558 g, 7.230 mmol) in an aqueous NaOH solution (4.34 g NaOH in 15 ml water) was heated at reflux for 0.5 h before cooling and treatment with water (100 ml). The mixture was then heated to reflux again and the hot mixture filtered through a Buchner funnel. The filtrate was then acidified with conc. HCl and the resultant solid was filtered, washed with water (20 ml) and dried in vacuo to give the desired product (700 mg, 49%).
後処理
- temperaturewas heated
- temperatureat reflux for 0.5 h
- temperaturebefore cooling
- temperatureThe mixture was then heated
- temperatureto reflux again
- filtrationthe hot mixture filtered through a Buchner funnel
- filtrationthe resultant solid was filtered
- washwashed with water (20 ml)
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-c78787aec78f4aa7ab41a3355e617f86
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08071592B2
反応ノート
読み込み中…