Isopropyl isocyanate → 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea
反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH2:14])=[CH:7][CH:6]=1)[CH3:3].[CH:15]([N:18]=[C:19]=[O:20])([CH3:17])[CH3:16]>C(#N)C>[CH3:3][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH:14][C:19]([NH:18][CH:15]([CH3:17])[CH3:16])=[O:20])=[CH:7][CH:6]=1)[CH3:1]参加物
4
実験手順
2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) and isopropylisocyanate (0.89 g) were dissolved in acetonitrile and allowed to stand overnight. Solvents were removed and the residue recrystallised from methanol:ether to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea as crystals m.p. 65°-67° (2.8 g).
後処理
- customSolvents were removed
- customthe residue recrystallised from methanol
出典と根拠
- ORDレコード
- ord-ba9a62af5dc1452292d5c5c2f0e4d526
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04128658
反応ノート
読み込み中…