Acetic Acid → 2-Cyclohexen-1-one, 2,5,6-trimethyl-

HRID 65801

反応式

HRID 65801 の反応式
[CH:1](=[O:5])/[CH:2]=[CH:3]/[CH3:4].[CH2:6]([C:8]([CH2:10]C)=O)[CH3:7].C[O-].[Na+].[C:15](O)(=O)C>CO>[CH3:15][C:2]1[C:1](=[O:5])[CH:6]([CH3:7])[CH:8]([CH3:10])[CH2:4][CH:3]=1

参加物

6

反応物 4

HCID 176Acetic AcidHCID 7288Ethyl ketoneHCID 447466CrotonaldehydeHCID 10942334Sodium Methoxide

生成物 1

HCID 892642-Cyclohexen-1-one, 2,5,6-trimethyl-

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

70 g of crotonaldehyde is dripped in the course of one hour into a mixture of 400 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux and the reaction mixture is boiled for another half hour under reflux. The whole is neutralized with glacial acetic acid and the mixture obtained is filtered. 325 g of diethyl ketone is recovered by distillation of the filtrate; 55 g of 2,5,6-trimethyl-2-cyclohexen-1-one having a boiling point of from 74° to 76° C. at 12 mm Hg is obtained. The yield with reference to crotonaldehyde is 40%.

後処理

  1. temperatureunder reflux
  2. temperatureunder reflux
  3. customthe mixture obtained
  4. filtrationis filtered
  5. distillation325 g of diethyl ketone is recovered by distillation of the filtrate

出典と根拠

ORDレコード
ord-8d2ac9117a644f9d8f308d3ba69ae5b1
出典データセット
uspto-grants-1978_12
特許番号
US04128728

関連ノート

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