Ethyl ketone → 2-Cyclohexen-1-one, 2,5,6-trimethyl-

HRID 65803

反応式

HRID 65803 の反応式
CO[CH:3]([CH3:7])[CH2:4][CH:5]=[O:6].[CH2:8]([C:10]([CH2:12]C)=O)[CH3:9].[CH3:14][O-].[Na+]>CO>[CH3:14][C:4]1[C:5](=[O:6])[CH:8]([CH3:9])[CH:10]([CH3:12])[CH2:7][CH:3]=1

参加物

5

反応物 3

HCID 7288Ethyl ketoneHCID 980403-MethoxybutyraldehydeHCID 10942334Sodium Methoxide

生成物 1

HCID 892642-Cyclohexen-1-one, 2,5,6-trimethyl-収率 56%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

102 g of β-methoxybutyraldehyde is dripped in the course of one hour into a mixture of 500 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux. The whole is then heated for another hour under reflux. The reaction mixture is processed as described in Example 2. 77 g of 2,5,6-trimethyl-2-cyclohexen-1-one is obtained, i.e. a 56% yield with reference to β-methoxybutyraldehyde.

後処理

  1. temperatureunder reflux
  2. temperatureThe whole is then heated for another hour
  3. temperatureunder reflux

出典と根拠

ORDレコード
ord-9c14c87cead5429790577056f90c7ce5
出典データセット
uspto-grants-1978_12
特許番号
US04128728

関連ノート

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