2-Aminopyridine → N-Pyridin-2-yl-N'-1,2,3-thiadiazol-5-ylurea
反応式
O([C:8]([NH:10][C:11]1[S:15][N:14]=[N:13][CH:12]=1)=[O:9])C1C=CC=CC=1.[NH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1>CC(C)=O>[N:18]1[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=1[NH:16][C:8]([NH:10][C:11]1[S:15][N:14]=[N:13][CH:12]=1)=[O:9]参加物
4
実験手順
16.5 g (0.075 mol) 5-phenoxycarbonylamino-1,2,3-thiadiazole are suspended in 150 ml acetone and reacted with 9.4 g (0.1 mol) of 2-aminopyridine. The reaction mass is then refluxed for 3 hours. After cooling to room temperature the formed light brown crystals are removed by suction and dried. They are then recrystallized from ethanol. There is thus obtained the above noted title compound (compound No. 1).
後処理
- temperatureThe reaction mass is then refluxed for 3 hours
- customare removed by suction
- customdried
- customThey are then recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-9cd989bd400d4486b4cc1ba3d1381258
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04130414
反応ノート
読み込み中…