cis-4-Acetyl-2-oxa-4-aza-bicyclo-[4.3.0]non-7-en-3-one → cis-4-Acetyl-2-oxa-4-aza-bicyclo[4.3.0]nonan-3-one
反応式
[C:1]([N:4]1[CH2:12][C@@H:11]2[C@@H:7]([CH2:8][CH:9]=[CH:10]2)[O:6][C:5]1=[O:13])(=[O:3])[CH3:2]>CO.[Pt](=O)=O>[C:1]([N:4]1[CH2:12][C@@H:11]2[C@@H:7]([CH2:8][CH2:9][CH2:10]2)[O:6][C:5]1=[O:13])(=[O:3])[CH3:2]参加物
4
実験手順
181 g (1.0 mol) of cis-4-acetyl-2-oxa-4-aza-bicyclo-[4.3.0]non-7-en-3-one, in 1,000 ml of methanol, are hydrogenated at 25° C. under normal pressure in the presence of platinum dioxide. After the catalyst has been filtered off, the reaction solution is freed from the solvent by distillation. Distillation of the residue gives 183 g (100% of theory) of cis-4-acetyl-2-oxa-4-aza-bicyclo[4.3.0]nonan-3-one (melting point: 80°-83° C.; from methanol).
後処理
- filtrationAfter the catalyst has been filtered off
- distillationthe reaction solution is freed from the solvent by distillation
- distillationDistillation of the residue
出典と根拠
- ORDレコード
- ord-1e93781ef9fc4de5b719cb817a928260
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04130563
反応ノート
読み込み中…