N-bromobutanimide → (S)-N1-(5-(1-methyl-1H-indazol-6-yl)thiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine

反応式

N[C@:2]1([NH:21][CH2:22][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][C:28](Cl)=[CH:27][CH:26]=2)[NH:6][C:5](C(F)(F)F)=[C:4]([C:11]2[CH:12]=[C:13]3[C:18](=[CH:19][CH:20]=2)[CH:17]=[N:16]C=C3)[S:3]1.BrC1SC(N)=NC=1[C:39]([F:42])([F:41])[F:40].FC(F)(F)[C:45]1[N:46]=C(N)SC=1.Br[N:54]1C(=O)CCC1=O>>[NH2:54][C@@H:23]([CH2:24][C:25]1[CH:26]=[CH:27][C:28]([C:39]([F:42])([F:41])[F:40])=[CH:29][CH:30]=1)[CH2:22][NH:21][C:2]1[S:3][C:4]([C:11]2[CH:12]=[C:13]3[C:18]([CH:17]=[N:16][N:46]3[CH3:45])=[CH:19][CH:20]=2)=[CH:5][N:6]=1