Propionic Acid → 6,7-dichloro-4-(4-fluoro-3-(4-propionylpiperazine-1-carbonyl)benzyl)pyrrolo[1,2-a]pyrazin-1(2H)-one

HRID 662922

反応式

[CH3:1][CH2:2][C:3]([OH:4])=[O:5].[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:39][c:40]1[c:41]([Cl:66])[cH:42][c:43]2[n:44]1[c:45]([CH2:50][c:51]1[cH:52][c:53]([C:58](=[O:59])[N:60]3[CH2:61][CH2:62][NH:63][CH2:64][CH2:65]3)[c:54]([F:57])[cH:55][cH:56]1)[cH:46][nH:47][c:48]2=[O:49].[O:67]=[CH:68][N:69]([CH3:70])[CH3:71].[P-:6]([F:7])([F:8])([F:9])([F:10])([F:11])[F:12].[n:13]1([O:14][C:15]([N:16]([CH3:17])[CH3:18])=[N+:19]([CH3:20])[CH3:21])[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2[n:28][n:29]1>>[CH3:1][CH2:2][C:3](=[O:5])[N:63]1[CH2:62][CH2:61][N:60]([C:58]([c:53]2[cH:52][c:51]([CH2:50][c:45]3[n:44]4[c:40]([Cl:39])[c:41]([Cl:66])[cH:42][c:43]4[c:48](=[O:49])[nH:47][cH:46]3)[cH:56][cH:55][c:54]2[F:57])=[O:59])[CH2:65][CH2:64]1