Water → 2-Chloro-1-(2-methoxyphenyl)ethan-1-ol
反応式
CO[CH:3]([Cl:12])[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].O.[BH4-].[Na+].[O:16]1CCOC[CH2:17]1>>[Cl:12][CH2:3][CH:4]([OH:5])[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:11]=1[O:16][CH3:17]参加物
5
実験手順
1.7 g of 2-methoxy-α-chloroacetophenone are dissolved in 30 ml of dioxane, and 12 ml of water are added thereto. 600 mg of sodium borohydride are added gradually to the solution at 10° to 20° C. Then, the mixture is treated in the same manner as described in Example 2-(1). 1.4 g of α-chloromethyl-2-methoxybenzylalcohol are obtained as a crude oil.
後処理
- additionThen, the mixture is treated in the same manner
出典と根拠
- ORDレコード
- ord-3f9bca722ccc4b99a3df1596ea863917
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04131686
反応ノート
読み込み中…