6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol

HRID 66354

反応式

HRID 66354 の反応式
[OH:1][C:2]1[C:3]([N+:9]([O-])=O)=[N:4][C:5]([CH3:8])=[CH:6][CH:7]=1>[Pd].CO>[NH2:9][C:3]1[C:2]([OH:1])=[CH:7][CH:6]=[C:5]([CH3:8])[N:4]=1

参加物

4

反応物 1

HCID 848016-Methyl-2-nitropyridin-3-ol

生成物 1

HCID 885002-Amino-6-methylpyridin-3-ol

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next step.

後処理

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated to dryness

出典と根拠

ORDレコード
ord-4289872c8b854b6d8388299f54433d7b
出典データセット
uspto-grants-1978_12
特許番号
US04131677

関連ノート

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