Decylamine → N-Decyl-3-phenyl-3-(4-nitrophenyl)propenamide

HRID 66618

反応式

HRID 66618 の反応式
[CH2:1]([NH2:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:12]1([C:18]([C:23]2[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][CH:24]=2)=[CH:19][C:20](Cl)=[O:21])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>O1CCCC1>[CH2:1]([NH:11][C:20](=[O:21])[CH:19]=[C:18]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:23]1[CH:24]=[CH:25][C:26]([N+:29]([O-:31])=[O:30])=[CH:27][CH:28]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

4

反応物 2

HCID 8916DecylamineHCID 545299323-Phenyl-3-(4-nitrophenyl)propenoyl chloride

生成物 1

HCID 53643429N-Decyl-3-phenyl-3-(4-nitrophenyl)propenamide

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To a stirred solution of 5.89 g. of decylamine in 25 ml. of tetrahydrofuran was added a solution of 4.89 g. of 3-phenyl-3-(4-nitrophenyl)propenoyl chloride in 25 ml. of tetrahydrofuran, dropwise, during 20 minutes, at ice-bath temperature. The solvent was removed by evaporation in vacuo and the residue was partitioned between ethyl acetate and water. The layers were separated, and the ethyl acetate layer was washed with water, dried using sodium sulfate, and then evaporated in vacuo. This afforded 5.6 g. of the title compound, m.p. 91°-93° C.

後処理

  1. customThe solvent was removed by evaporation in vacuo
  2. customthe residue was partitioned between ethyl acetate and water
  3. customThe layers were separated
  4. washthe ethyl acetate layer was washed with water
  5. customdried
  6. customevaporated in vacuo

出典と根拠

ORDレコード
ord-95afdeb0788641779bcbb9277debbf05
出典データセット
uspto-grants-1982_08
特許番号
US04342781

関連ノート

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