1-Nitropropane → 1-Hydroxy-2-Ethylbenzimidazole-3-Oxide

HRID 66956

反応式

HRID 66956 の反応式
[N+]([CH2:4][CH2:5][CH3:6])([O-])=O.[CH:7]1[CH:15]=[CH:14][C:13]2[C:9](=[N:10][O:11][N+:12]=2[O-:16])[CH:8]=1.C(NCC)C>O1CCCC1>[OH:11][N:10]1[C:9]2[CH:8]=[CH:7][CH:15]=[CH:14][C:13]=2[N+:12]([O-:16])=[C:4]1[CH2:5][CH3:6]

参加物

5

反応物 3

HCID 79031-NitropropaneHCID 8021DiethylamineHCID 68075Benzofuroxan

生成物 1

HCID 145490291-Hydroxy-2-Ethylbenzimidazole-3-Oxide

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

To a mixture containing 1-nitropropane (10.7 g., 0.12 moles), benzofuroxan (13.6 g., 0.10 moles) and tetrahydrofuran (50 ml.) is added dropwise diethylamine (8.7 g., 0.12 moles). The reaction temperature rises almost to reflux on addition of amine. Upon completion, the mixture is allowed to cool and then sit overnight.

後処理

  1. temperatureto cool

出典と根拠

ORDレコード
ord-5eee42ca1ae243628b6315c46337862b
出典データセット
uspto-grants-1982_08
特許番号
US04343942

関連ノート

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