Tetrahydrofuran → (4-((2-Amino-4-chloro-6-methylpyrimidin-5-yl)methyl)-3-fluorophenyl)methanol

反応式

[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][CH:2]([CH2:3][AlH:4][CH2:5][CH:6]([CH3:7])[CH3:8])[CH3:9].[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[NH2:10][c:11]1[n:12][c:13]([CH3:30])[c:14]([CH2:18][c:19]2[c:20]([F:29])[cH:21][c:22]([C:23](=[O:24])[O:25][CH3:26])[cH:27][cH:28]2)[c:15]([Cl:17])[n:16]1>>[NH2:10][c:11]1[n:12][c:13]([CH3:30])[c:14]([CH2:18][c:19]2[c:20]([F:29])[cH:21][c:22]([CH2:23][OH:24])[cH:27][cH:28]2)[c:15]([Cl:17])[n:16]1