2-Pentanone → 1-Bromo-trans-1-octen-3-one

HRID 66999

反応式

HRID 66999 の反応式
Cl/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[Br-:11].[Li+].CC(=O)CCC>>[Br:11]/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

参加物

4

反応物 3

HCID 78952-PentanoneHCID 82050Lithium BromideHCID 110410031-Chloro-trans-1-octen-3-one

生成物 1

HCID 117903381-Bromo-trans-1-octen-3-one

実験手順

A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and ether. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.

後処理

  1. additionA mixture of 68.0 g
  2. temperaturecooled
  3. custompartitioned between ice water and ether
  4. washThe organic phase is washed with water and saturated brine
  5. dry with materialdried (NaSO4)
  6. customevaporated to an oil
  7. customThis material is used directly without purification

出典と根拠

ORDレコード
ord-8fa867cbcf20417ab9d4d032eb2d0c3c
出典データセット
uspto-grants-1982_08
特許番号
US04343949

関連ノート

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