Dimethyl Sulfoxide → 5-fluoro-2',2'-dimethylspiro[1H-indole-3,1'-cyclopropane]-2-one

反応式

[CH3:24][S:25](=[O:26])[CH3:27].[CH3:4][S+:5]([CH3:6])([CH3:7])=[O:8].[F:9][c:10]1[cH:11][c:12]2[c:16]([cH:17][cH:18]1)[NH:15][C:14](=[O:19])[C:13]2=[C:20]([CH3:21])[CH3:22].[H-:2].[I-:3].[Na+:1].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH2:23]>>[CH3:4][C:20]1([CH3:22])[C:13]2([c:12]3[cH:11][c:10]([F:9])[cH:18][cH:17][c:16]3[NH:15][C:14]2=[O:19])[CH2:21]1