Thionyl Chloride → 6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

HRID 67099ノート

反応式

HRID 67099 の反応式
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13](O)=[O:14])[C:5]2=[O:16].S(Cl)([Cl:19])=O>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13]([Cl:19])=[O:14])[C:5]2=[O:16]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 122007766,7-Dihydroxychromon-3-carboxylic acid

生成物 1

HCID 127657576,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

実験手順

6,7-Dihydroxychromone-3-carboxylic acid (888 mg) and 25 ml of thionyl chloride were refluxed for one hour. Then, the thionyl chloride was removed by distillation, and after benzene was added, further distillation was conducted. Dichloromethane was added into the residue for solidification, whereby the desired product (719 mg) was obtained.

後処理

  1. customThen, the thionyl chloride was removed by distillation
  2. additionafter benzene was added
  3. distillationfurther distillation
  4. additionDichloromethane was added into the residue for solidification, whereby the desired product (719 mg)
  5. customwas obtained

出典と根拠

ORDレコード
ord-63fbe7f0b4634b799b24b98090e97e11
出典データセット
uspto-grants-1982_08
特許番号
US04344944

反応ノート

読み込み中…