Thionyl Chloride → 7,8-Dihydroxychromone-3-carbonyl chloride

HRID 67100ノート

反応式

HRID 67100 の反応式
[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13](O)=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1.S(Cl)([Cl:19])=O>>[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13]([Cl:19])=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 24386Thionyl Chloride2 回HCID 127658447,8-Dihydroxychromone-3-carboxylic acid

生成物 1

HCID 130830427,8-Dihydroxychromone-3-carbonyl chloride

実験手順

7,8-Dihydroxychromone-3-carboxylic acid (6.6 g) together with thionyl chloride (25 ml) were refluxed for one hour. Certain unreacted thionyl chloride remained in the reaction mixture was distilled off, and after addition of benzene to the residue, the mixture was again subjected to distillation. To the residue was added n-hexane to cause solidification of the residue. The solid matter thus formed was recovered by filtration. There was thus obtained the desired product (7.2 g).

後処理

  1. distillationwas distilled off
  2. additionafter addition of benzene to the residue
  3. distillationthe mixture was again subjected to distillation
  4. additionTo the residue was added n-hexane
  5. customThe solid matter thus formed
  6. filtrationwas recovered by filtration

出典と根拠

ORDレコード
ord-a051ed285acf4dad8ab181cc635d3748
出典データセット
uspto-grants-1982_08
特許番号
US04344944

反応ノート

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