3-Nitro-p-cresol → 3-Amino-p-cresol
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([OH:11])[CH:7]=[CH:8][C:9]=1[CH3:10])([O-])=O.[H][H]>[Ni].O1CCCC1>[NH2:1][C:4]1[CH:5]=[C:6]([OH:11])[CH:7]=[CH:8][C:9]=1[CH3:10]参加物
5
実験手順
70 g of 3-nitro-4-methylphenol, prepared according to German Offenalegungschrift No. 2,213,568, 200 ml of tetrahydrofuran and 2 g of activated Raney nickel catalyst were placed in a Parr bomb. The mixture was shaken for 3.5 hours under 60 p.s.i. hydrogen pressure. The mixture then was filtered and the solvent was evaporated from the filtrate. The residue was recrystallized from ether to give 3-amino-4-methylphenol (3A), as a grey solid, mp: 145°-148° C.
後処理
- filtrationThe mixture then was filtered
- customthe solvent was evaporated from the filtrate
- customThe residue was recrystallized from ether
出典と根拠
- ORDレコード
- ord-2a417ce8477b47ffb0400faad8e9f2d7
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04345077
反応ノート
読み込み中…