cis-4-(3-Chlorophenyl)-but-3-enylamine → 4-(3-Chlorophenyl)butan-1-amine

HRID 6721

反応式

HRID 6721 の反応式
[Cl:1][C:2]1[CH:3]=[C:4](/[CH:8]=[CH:9]\[CH2:10][CH2:11][NH2:12])[CH:5]=[CH:6][CH:7]=1.[H][H]>CO.O.[Pt](=O)=O>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[CH:5]=[CH:6][CH:7]=1

参加物

5

反応物 2

HCID 58679830cis-4-(3-Chlorophenyl)-but-3-enylamineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 106550714-(3-Chlorophenyl)butan-1-amine収率 74.2%

試薬・触媒・溶媒 2

HCID 11139377Platinum dioxide monohydrate触媒HCID 887Methanol溶媒

実験手順

A solution of cis-4-(3-chlorophenyl)-but-3-enylamine (1.2 g) in 20 mL methanol was added to platinum(IV) oxide monohydrate (0.12 g). The mixture was stirred under 1 atm of hydrogen for 16 h. The mixture was filtered through celite, and the methanol was removed in vacuo to yield 0.9 g of 4-(3-chlorophenyl)-butylamine.

後処理

  1. filtrationThe mixture was filtered through celite
  2. customthe methanol was removed in vacuo

出典と根拠

ORDレコード
ord-6eda0c359052479e89b251fa31711b9d
出典データセット
uspto-grants-2006_08
特許番号
US07084154B2

関連ノート

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