Sarcosine → N-methyl-N-carboxymethyl-N'-phenylurea
反応式
[CH3:1][NH:2][CH2:3][C:4]([OH:6])=[O:5].[OH-].[Na+].[C:9]1([N:15]=[C:16]=[O:17])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>O>[CH3:1][N:2]([CH2:3][C:4]([OH:6])=[O:5])[C:16]([NH:15][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:17]参加物
5
反応条件
- 温度
- 24 °C
実験手順
To a stirred solution of 70 g. of N-methylaminoacetic acid in 500 ml. of water containing 70 g. of sodium hydroxide were added portion-wise over twenty minutes 100 g. of phenyl isocyanate. Following complete addition, the aqueous reaction mixture was stirred at 24° C. for two hours. The mixture was then filtered and the filtrate was acidified to pH 2 by the addition of conc. hydrochloric acid. The precipitate which formed was collected by filtration to provide N-methyl-N-hydroxycarbonylmethyl-N'-phenylurea.
後処理
- additionaddition
- filtrationThe mixture was then filtered
- additionthe filtrate was acidified to pH 2 by the addition of conc. hydrochloric acid
- customThe precipitate which formed
- filtrationwas collected by filtration
出典と根拠
- ORDレコード
- ord-f3856926245047b18dba8d48c55b3f7b
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04345936
反応ノート
読み込み中…