Dichloromethane → N-[4-(3,4,5,6-Tetrahydro-2H-[1,2']bipyrazinyl-3'-yl)-benzyl]-acetamide

反応式

[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][N:18]([c:21]2[n:22][cH:23][cH:24][n:25][c:26]2-[c:27]2[cH:28][cH:29][c:30]([CH2:33][NH:34][C:35]([CH3:36])=[O:37])[cH:31][cH:32]2)[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[Cl:38][CH2:39][Cl:40].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][N:18]([c:21]2[n:22][cH:23][cH:24][n:25][c:26]2-[c:27]2[cH:28][cH:29][c:30]([CH2:33][NH:34][C:35]([CH3:36])=[O:37])[cH:31][cH:32]2)[CH2:19][CH2:20]1

参加物

反応物 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 685946133'-[4-(Acetylamino-methyl)-phenyl]-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid tert-butyl ester

生成物 1

HCID 68595017N-[4-(3,4,5,6-Tetrahydro-2H-[1,2']bipyrazinyl-3'-yl)-benzyl]-acetamide

出典と根拠

ORDレコード: ord-3865d5cdea844cfd93b555b072755235
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…