Lauric Acid → HCID 53773609、化合物

HRID 67669

反応式

HRID 67669 の反応式
[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH2:7].[C:8]([O:14]CC)(=O)[CH2:9][C:10]([CH3:12])=O.[C:17](O)(=[O:29])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>>[C:17]([O:1][CH2:2][CH2:3][N:4]1[C:8](=[O:14])[CH2:9][C:10]([CH3:12])=[N:7][CH2:6][CH2:5]1)(=[O:29])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

参加物

4

反応物 3

HCID 3893Lauric AcidHCID 8112N-(2-Hydroxyethyl)ethylenediamineHCID 8868Ethyl Acetoacetate

生成物 1

HCID 53773609HCID 53773609、化合物

実験手順

Into an apparatus similar to that in Example 1, were charged 104.2 g (1 mole) of N-hydroxyethylethylenediamine and 130.1 g (1 mole) of ethyl acetoacetate. At 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off. Then, after addition of 200.3 g (1 mole) of lauric acid, the esterification was effected at 200° to 210° C. to distil off 18 g of water and to obtain 4-lauroyloxyethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

後処理

  1. distillationAt 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off
  2. customwas effected at 200° to 210° C.
  3. customto distil off 18 g of water

出典と根拠

ORDレコード
ord-3c9d7ed1386a42abb1f96e3b7a2d42d7
出典データセット
uspto-grants-1982_08
特許番号
US04346087

関連ノート

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