Ethyl bromoacetate → 3-Methyl-4-oxo-2-phenyliminothiazolidine hydrobromide

HRID 67782

反応式

HRID 67782 の反応式
[Br:1]CC([O:5][CH2:6][CH3:7])=O.[CH3:8][NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[S:11]>CC(C)=O>[BrH:1].[CH3:8][N:9]1[C:6](=[O:5])[CH2:7][S:11][C:10]1=[N:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

4

反応物 2

HCID 7748Ethyl bromoacetateHCID 6982941-Methyl-3-phenylthiourea

生成物 1

HCID 205271953-Methyl-4-oxo-2-phenyliminothiazolidine hydrobromide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

10 g of ethyl bromoacetate and 9.95 g of 1-methyl-3-phenylthiourea in 150 ml of acetone are boiled for 1 hour under a reflux condenser. The reaction mixture is allowed to cool and the crystals are filtered off and washed with acetone. Melting point 212°-215° C.

後処理

  1. temperatureto cool
  2. filtrationthe crystals are filtered off
  3. washwashed with acetone

出典と根拠

ORDレコード
ord-807f3c22deb64f20afe079763f77af03
出典データセット
uspto-grants-1982_08
特許番号
US04346088

関連ノート

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