Phosgene → HCID 178484191、化合物

HRID 67785

反応式

HRID 67785 の反応式
C(Cl)([Cl:3])=O.O1CCCC1.[CH3:10][NH:11][C:12]([NH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=S>CN(C)C=O>[ClH:3].[CH3:10][NH:11][C:12]([Cl:3])=[N:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

参加物

5

反応物 3

HCID 6371Phosgene2 回HCID 8028TetrahydrofuranHCID 6982941-Methyl-3-phenylthiourea

生成物 1

HCID 178484191HCID 178484191、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

After passing 6.3 g of phosgene into 40 ml of absolute tetrahydrofuran at room temperature, 8 g of 1-methyl-3-phenylthiourea are added, with stirring, the color of the suspension changing instantaneously to yellow. After adding 0.5 ml of dimethylformamide, the mixture is stirred for 20 hours at room temperature, nitrogen is then passed through the reaction mixture for about 30 minutes, in order to drive off the phosgene, and the crystals are filtered off and washed with tetrahydrofuran. Crystals with a melting point of 169° C. (with decomposition).

後処理

  1. customat room temperature
  2. stirringthe mixture is stirred for 20 hours at room temperature
  3. filtrationthe crystals are filtered off
  4. washwashed with tetrahydrofuran

出典と根拠

ORDレコード
ord-0f79ccd029194271bff947b0b7abc7ea
出典データセット
uspto-grants-1982_08
特許番号
US04346088

関連ノート

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