Tetrahydrofuran → 4-Hydroxy-4-(3-methylsulfanylphenyl)-piperidin-1-carboxylic acid tert-butyl ester

反応式

[Br:1][c:2]1[cH:3][c:4]([S:8][CH3:9])[cH:5][cH:6][cH:7]1.[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][C:25](=[O:28])[CH2:26][CH2:27]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14]>>[c:2]1([C:25]2([OH:28])[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]2)[cH:3][c:4]([S:8][CH3:9])[cH:5][cH:6][cH:7]1