Diethyl Ether → Ethyl dodecane hydroximate

HRID 67945

反応式

HRID 67945 の反応式
[Cl-].O[NH3+].CC[O:6]CC.[CH2:9]([O:11][C:12](=[NH:24])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH3:10]>O>[C:12](=[N:24][OH:6])([O:11][CH2:9][CH3:10])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

参加物

5

反応物 3

HCID 3283Diethyl EtherHCID 21645Hydroxylamine HClHCID 3442835Ethyldodecaneimidate

生成物 1

HCID 86738559Ethyl dodecane hydroximate収率 77%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
2 °C

実験手順

A mixture containing fourteen grams of hydroxylammonium chloride dissolved in 100 ml of water was added to 100 ml of ether in a 250 ml flask. The resulting mixture was cooled to 2° C. and 45.4 g of ethyldodecaneimidate were added to the mixture with stirring. The reaction mixture was stirred for an additional 30 minutes at 2° C. The layers were separated and the aqueous layer was extracted three times with 75 ml of ether. The ether layer and washings were combined and then dried over sodium sulfate and concentrated to yield 37.3 g (77% yield) of ethyl dodecane hydroximate as a white, solid substance. IR and NMR analyses confirmed the structure.

後処理

  1. stirringThe reaction mixture was stirred for an additional 30 minutes at 2° C
  2. customThe layers were separated
  3. extractionthe aqueous layer was extracted three times with 75 ml of ether
  4. dry with materialdried over sodium sulfate
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-e15a47277379479ea60e7f0627918e63
出典データセット
uspto-grants-1982_08
特許番号
US04347342

関連ノート

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