N-ethyl-3-methyl-6-nitroquinolin-2-amine → n2-Ethyl-3-methylquinoline-2.6-diamine

HRID 6806

反応式

HRID 6806 の反応式
[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([N+:15]([O-])=O)[CH:10]=2)[N:5]=1)[CH3:2]>CO.[Pt]=O>[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:15])[CH:10]=2)[N:5]=1)[CH3:2]

参加物

4

反応物 1

HCID 22018880N-ethyl-3-methyl-6-nitroquinolin-2-amine

生成物 1

HCID 85837566n2-Ethyl-3-methylquinoline-2.6-diamine

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 887Methanol溶媒

実験手順

The product (0.8 g) of Step B and platinum oxide on carbon (˜80 mg) was suspended in methanol. The resulting mixture was hydrogenated at 50 PSI for 1 h. The reaction mixture was filtered through filter aid and the solvent removed under vacuum to afford the product, which was used without further purification.

後処理

  1. filtrationThe reaction mixture was filtered
  2. filtrationthrough filter aid
  3. customthe solvent removed under vacuum
  4. customto afford the product, which
  5. customwas used without further purification

出典と根拠

ORDレコード
ord-bc1ae466ad6d421a8c6e6bc08d31abd8
出典データセット
uspto-grants-2006_08
特許番号
US07084156B2

関連ノート

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