Pyridine → 7-[3-[(Dimethylamino)methyl]-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

反応式

[CH3:19][N:20]([CH3:21])[CH2:22][CH:23]1[NH:24][CH2:25][CH2:26][NH:27][CH2:28]1.[Cl:1][c:2]1[c:3]([F:18])[cH:4][c:5]2[c:6](=[O:17])[c:7]([C:14](=[O:15])[OH:16])[cH:8][n:9]([CH2:12][CH3:13])[c:10]2[cH:11]1.[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[c:2]1([N:27]2[CH2:26][CH2:25][NH:24][CH:23]([CH2:22][N:20]([CH3:19])[CH3:21])[CH2:28]2)[c:3]([F:18])[cH:4][c:5]2[c:6](=[O:17])[c:7]([C:14](=[O:15])[OH:16])[cH:8][n:9]([CH2:12][CH3:13])[c:10]2[cH:11]1

参加物

反応物 3

HCID 1049Pyridine

HCID 4831697-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

HCID 14664185N,N-dimethyl-2-piperazinemethanamine

生成物 1

HCID 148393477-[3-[(Dimethylamino)methyl]-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

出典と根拠

ORDレコード: ord-a1cccf62d57e487aa7dbac7ae95138b3
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…