Trifluoroacetic acid → 4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

反応式

[CH2:8]([CH3:9])[C:10]1([OH:29])[C:11](=[O:28])[O:12][CH2:13][c:14]2[c:15](=[O:27])[n:16]3[c:20]([cH:21][c:22]21)[C:19]1([CH2:18][CH2:17]3)[O:23][CH2:26][CH2:25][O:24]1.[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH2:8]([CH3:9])[C:10]1([OH:29])[C:11](=[O:28])[O:12][CH2:13][c:14]2[c:15](=[O:27])[n:16]3[c:20]([cH:21][c:22]21)[C:19](=[O:23])[CH2:18][CH2:17]3

参加物

反応物 3

HCID 6422Trifluoroacetic acid

HCID 8857Ethyl Acetate

HCID 3641314'-Ethyl-4'-hydroxy-7',8'-dihydrospiro[[1,3]dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'(1'H,4'H)-dione

生成物 1

HCID 3598494-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

出典と根拠

ORDレコード: ord-eed8d4f97412428bbf404498163ae236
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…