Thionyl Chloride → 4-(4-Methyl-oxazol-5-yl)-benzoyl chloride

HRID 68762ノート

反応式

HRID 68762 の反応式
S(Cl)([Cl:3])=O.[CH3:5][C:6]1[N:7]=[CH:8][O:9][C:10]=1[C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1>ClCCl>[CH3:5][C:6]1[N:7]=[CH:8][O:9][C:10]=1[C:11]1[CH:19]=[CH:18][C:14]([C:15]([Cl:3])=[O:16])=[CH:13][CH:12]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 682900554-(4-Methyloxazol-5-yl)benzoic acid

生成物 1

HCID 866782114-(4-Methyl-oxazol-5-yl)-benzoyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Thionyl chloride (2.00 mL) is added to 4-(4-methyl-oxazol-5-yl)-benzoic acid (400 mg) in dichloromethane (5 mL) and the mixture is stirred for two days at room temperature. The solvent is evaporated to give the title compound, which is used without further purification for the next reaction step.

後処理

  1. customThe solvent is evaporated

出典と根拠

ORDレコード
ord-00937668ffff45a6bfe0b720f329e30d
出典データセット
uspto-grants-2014_09
特許番号
US08822471B2

反応ノート

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